Signant’s neuroscience team and CNS experts presented scientific posters at the 2022 Autumn Conference hosted by the International Society for CNS Clinical Trials and Methodology.  

The posters presented original research on a variety of topics related to the Positive and Negative Syndrome Scale (PANSS), including the potential impact of baseline PANSS symptom domain severity on interview duration and abnormal patterns of variability such as post-baseline 30/30 PANSS identical ratings. Separately, we examined whether a 10-item PANSS optimized for pediatric trials would perform similarly to the 30-item PANSS in an independent placebo-controlled multi-site trial. 

Other posters delved into research on the Mini-Mental State Exam (MMSE) for dementia, including the association between the MMSE interview duration and the presence of administration and/or scoring errors, and the impact of the number of per rater MMSE administrations on the probability of identifying an administration or scoring MMSE error. 

Browse through each poster below and meet our experts to learn how Signant has been optimizing CNS clinical research for over 20 years.  

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