Featured in Applied Clinical Trials, this article discusses how digital technology enables reliable and remote data collection. Due to the recent COVID-19 pandemic, sponsors are urged to have strategies and contingencies in place at the outset of new studies or re-opening of halted studies.

Before starting a clinical trial, special considerations should be taken regarding:

• Protocols & study visits
• Equipment & logistics
• Remote healthcare
• Training
• Standardization

These considerations can help manage uncertainty and improve patient engagement.