Signant’s neuroscience team and CNS experts presented scientific posters at the 2022 Alzheimer’s Association International Conference in San Diego, California, from July 31-August 4.   

Two of the posters presented original research on the geo-cultural influence on Clinical Dementia Rating Sum of Box (CDR-SB) and Mini-Mental State Examination (MMSE) scores. One of them found that average change in CDR-SB scores but not MMSE total scores significantly differ across geo-cultural regions. The other poster found that the strength of the correlation between CDR-SB scores and MMSE total scores varied significantly by geo-cultural regions.  Other poster topics explored the impact of protocol design on the relationship between baseline ADAS-Cog Word Recall and MMSE total score, and on MMSE blinded change one year after randomization in early AD clinical trials. 

Browse through each poster below and meet our experts to learn how Signant has been optimizing Alzheimer’s dementia clinical research for over 20 years. 

Erica Appleman, Todd Feaster, John Harrison, Rujvi Kamat, Alan Kott, Sayaka Machizawa, David Miller, Jessica Stenclik, Zinan Chen Tackett, Xingmei Wang  

Signant Health

Signant Health is the evidence generation company. We are focused on leveraging software, deep therapeutic and scientific knowledge, and operational expertise to consistently generate quality evidence for clinical studies across traditional, virtual, and hybrid trial models. For more than 20 years, over 400 sponsors and CROs of all sizes – including all of Top 20 pharma – have trusted Signant Health solutions for remote and site-based eCOA, eConsent, IRT, supply chain management, and data quality analytics.

Recent Posts

Scientific Advisory

ISCTM 2022: Scientific Posters Compilation

Learn more

Clinical Supplies

Application Programming Interfaces (APIs) in Randomization and Trial Supply Management (RTSM)

Learn more

eCOA

5 Recommendations for Electronically Migrating and Implementing ClinROs

Learn more

eCOA

Innovation: Using Smartphone Sensors to Instrument At-Home Stair-Climbing Performance Tests

Learn more

Scientific Advisory

Get to Know the SME – Lew Fredane

Learn more