Outcome Solutions in Medical Research Date Published: Aug 10, 2020 Article A key challenge facing CNS clinical and medical research is in designing studies to demonstrate efficacy by obtaining a true drug-placebo difference. Readers will learn about how inaccurate ratings, mistakes, bias, protocol violations, and falsified data bring additional challenges. This article uses hypothetical protocol to illustrate how these common challenges put trials at risk. Signant Health’s Dr. Bill Byrom, Dr. Denis Curtin, Dr. David Daniel, Dr. Alan Kott, and Dr. Gary Sachs describe how digital solutions, like eCOA, can help. The team also make predictions on how novel approaches and technology will be used in the future to deliver a better patient experience. Download Now Share: LinkedInTweet Recommended Resources Article Conversation with Bill Byrom & Mariana Fontana: Measuring Aspects of Health in Heart Failure Research Dr. Bill Byrom, Principal, eCOA Science at Signant Health, recently had the pleasure of sitting downwith Professor Marianna Fontana, Professor... Download Now Article Conversation with Bill Byrom & Julian Gillmore: Increasing the Usefulness of COAs in Heart Failure Research Dr. Bill Byrom, Principal, eCOA Science at Signant Health, recently had the pleasure of sitting downwith Professor Julian Gillmore, Professor... Download Now Article Optimal COA Measurement Strategy in Modern Oncology Trials The inclusion of patient-reported outcomes (PRO) data in oncology medication labeling in the U.S. has been comparatively limited. Recent FDA... Read Now