A glowing light bulb full of ideas
The Signal

Expert insights and opinions on clinical research and drug development.

Expert insights and opinions on clinical research and drug development.

Signant Health’s Clinical Scientist Jennifer Olt Receives ISCTM New Investigator Award

Jennifer Olt, Ph.D., a Clinical Scientist from Signant Health’s Operations – Clinical Science team, accepted a 2022 New Investigator Award…

Patient-Reported Outcomes in Medical Device Trials – What We Can Learn From the FDA Guidance

Patient-reported outcomes data are increasingly collected in medical device clinical trials. In their strategic priorities document [1], the FDA’s Center…

Measurement Comparability of Electronic and Paper Administration of Visual Analogue Scales: A Review of Published Studies

Visual analogue scales (VASs) in clinical trials ask patients to mark a position on a horizontal line to reflect how…

Leveraging the Power of Real-Time Data Aggregation: Virtual Event Recap

Recently, Signant hosted a virtual event exploring topics in clinical data management. Introducing the concept of data aggregation underpinning Signant’s…

Dealing with Missing Data from Sensors and Wearables

The potential of using sensors and wearables in developing clinical trial measures to better understand the effects of new treatment…

The Winter Imagine Forum Recap

For Signant Health’s second Imagine Forum, we focused on how the industry can leverage direct-to-patient (DtP) clinical supply approaches to…

5 Tips for Success in Rare Disease Studies

Before you begin planning your rare disease study, it’s important to identify potential challenges. At Signant, we believe that the…

Clinical Data Fraud: Detection & Mitigation Strategies

One of the most compelling arguments for using electronic data capture methods for patient-reported outcome assessments (ePRO) is the ability to ensure and demonstrate data integrity. Electronic data collection allows study teams to use…

Webinar Recap: Applying Advanced Analytics to Overcome CNS Trial Challenges

If you missed Signant’s webinar on applying analytics to CNS clinical trials, you’re in luck – we’ve summarized the key…

The Center for Drug Evaluation’s (CDE) draft PRO guidance

In the landscape of rapidly growing numbers of pharmaceutical clinical trials in China, the Chinese Center for Drug Evaluation (CDE)…